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MTHFR Mutation Diagnosis

This is the story of my MTHFR mutation diagnosis, how it was discovered and what preliminary treatment plan I’ve been prescribed.

MTHFR Mutation Diagnosis

Hey all,

So… I had a consult with an obgyn today and was informed I tested positive for two copies of the C677T mutation Methylenetetrahydrofolatereductase (MTHFR). Basically my blood clots too much and I am not good at absorbing folate. At least that’s what they told me.

I guess that explains why I have had three miscarriages and have had bleeding in all four of my pregnancies.

MTHFR Treatment Plan

So far, the plan is to take aspirin and extra folate (for the rest of my life). I think I’m going to do this for three months starting now before I try to get pregnant again.

When I was pregnant with Gabriel I was very diligent about taking my prenatal vitamins before and during that pregnancy. With these last pregnancies (which I actually haven’t told you about yet until writing this blog post) I had been more lackadaisical before and during pregnancy about taking my vitamins. Is this what caused two of my miscarriages?

I could easily go down that path of feeling super guilty that I wasn’t diligent enough – but I won’t. I didn’t know any better, you know? I’ve forgiven myself today… and I’ll keep reminding myself in the days to come.

MTHFR High Risk Pregnancy

Right now I’m looking for information on if MTHFR risks me out of an out of hospital birth. I was talking to my obgyn and he seemed to think that I should have my baby in a hospital. He wasn’t very definitive in his answer (which of course, was that I should have my baby in a hospital) and I’m not exactly clear of the risks associated with a full-term pregnancy with a double copy of the MTHFR mutation.

Also, I’m interested in finding out what other treatment plans women have found to be helpful. Is the folate and aspirin enough?

So, If anybody has any information they want to pass on to me, that would be fantastic. Go ahead and comment in this post and maybe other women will find it helpful too.

MTHFR Mutation Diagnosis Relief

Honestly, I was really relieved to have found an answer of sorts to what the heck has been going on. I’m not upset at all, and am up for the challenge. Secretly, I’ve always wondered what it would be like (for me) to have a baby in a hospital. I think I could rock it, you know? I’d have to break out the big doula guns, of course. 🙂

So, there it is. This is what I have kept a secret for many, many months. I feel like today was the perfect time  to tell you about my miscarriages because now I have something to work with and towards.


Tuesday 11th of April 2017

Please don't just take folic acid without further research. It's not always good for people with MTHFR. It is an artificial form. Drug companies like to sell it I think because it's cheap and stable. We can't always avoid it because it is added to flour and many processed foods. But for some of us it can possibly build up and be toxic. If you can't convert it to folate because of methylation issues (ie MTHFR) then I think it's a risky choice. Be well.


Friday 4th of November 2011

I'm glad you finally have an answer. You are such a strong woman, I know you can conquer anything, and rock the crap out of a hospital birth.

Lindsey (Mother Rising)

Thursday 3rd of November 2011

Dwija - I love your blog! Thanks for stopping by. You can't overdose on folic acid, so it wouldn't hurt. If you do have a blood clotting problem you might consider aspirin too.

Holly - I'll stop on by babycenter. Thanks for all the information!

Leslee and Kristen - Thanks for the information!!

Holly Hansen

Thursday 3rd of November 2011


Almost every woman on Babycenter who has repeat pregnancy loss has MTHFR. It definitely cannot hurt to start folate supplemenatation as soon as possible.

Dwija {House Unseen}

Thursday 3rd of November 2011

Thank you for sharing your story! I am going to up my folic acid RIGHT NOW because I've also had 3 miscarriages plus bleeding in two of my pregnancies.

I've only had hospital births and although I know you could rock it, I'm not sure you could really enjoy it- the feeling trapped there after baby has arrived is a very frustrating feeling when you have little ones at home. You're just not allowed to leave until so and so does such and such tests...enough to make a mama crazy! For our next baby, I'm going to insist on a home birth :)